Prevalence of hypothyroidism among 1st trimester pregnant women in lower part of Assam: A pilot study
Diganta Das, Syed Javed Salman Chisty, Karabi Barman, Bharat Talukdar, Uddip Talukdar
Objective: This study was undertaken to know the prevalence of hypothyroidism among pregnant women in lower part of Assam. Methodology: The study was an out patient department (OPD) based prospective cohort, observational study. 500 pregnant women in first trimester between the age group of 18 to 35 years who are attending the Ante natal OPD of Fakhruddin Ali Ahmed Medical College, were included in the study. Serum thyroidstimulating hormone (TSH) estimation was done by the ADVIA Centaur CP/Chemiluminescence assay method. Results: 218 (43.6 %) out of 499 pregnant lady in their 1st trimester was suffering from hypothyroidism with mean TSH level 4.22 ±2.14 mIU/ml. No significant correlation between age and TSH were found in hypothyroid population. Conclusions: Thyroid disorders are common in pregnancy, and the most common disorder is subclinical hypothyroidism. Looking at the high percentage of abnormal TSH in pregnancies, universal screening should be considered, specially in this part of the country.