Disseminated intravascular coagulation in obstetrics
Rajib Kumar Bhattacharyya, Rumi Baruah, Dipankar Baruah
Disseminated Intravascular Coagulation (DIC) is an acute emergency characterized by inappropriate activation of coagulation and fibrinolytic system secondary phenomenon triggered by specific disorders such as abruptio placentae and amniotic fluid embolism due to release of thromboplastin intravascularly or endothelial damage resulting from pre-eclampsia and sepsis and manifested by severe bleeding. Diagnosis is often made from clinical manifestation and estimation of coagulation profile though histological diagnosis of fibrin deposits is the definitive feature of DIC. Basic principles of management include understanding the pathophysiology, elimination of underlying cause and replacement of lost blood and specific components.