Study of thyroid profile in pregnancy with perinatal outcome
Mahendra Patwari, Bharat Talukdar, Batiston Decruse Waanbah
Objectives: To assess the thyroid profile of pregnant women with comparison of the perinatal outcome in euthyroid and abnormal thyroid profile women. Methodology: This prospective cross sectional study was consisted of 150 women, of whom 75 were healthy normal pregnant women (Group A), other 75 were pregnant women with thyroid disorder (Group B). Results: Maximum thyroid disorder during pregnancy was subclinical hypothyroidism (68%). No statistically significant difference in relation to gestational age at delivery in cases of Group A and Group B were seen. 48% of caesarean delivery was in Group B in comparison to Group A (24%) (p<0.05). 2.67% cases in Group A and 6.67% cases in Group B delivered IUD baby. The mean birth weight of newborn of Group B and Group A were 2.57±0.50 kg and 2.92±0.60 kg respectively (p<0.001). The ≤ 6 APGAR score of newborn at 1 and 5 minutes were noted 30.43% and 18.84% in Group B as comparison to 8.22% and 4.11% cases of Group A which was statistically significant (p<0.01). Conclusion: Present study concludes that there is significant association between thyroid disorders and adverse perinatal outcome.