To study the efficacy of misoprostol compared with methyl ergometrine for prevention of postpartum haemorrhage
Objective: Present study was conducted to study the safety and efficacy of misoprostol and methyl ergometrine when used in the prevention of postpartum haemorrhage (PPH). Methodology: In a controlled trial, 100 pregnant women who had a vaginal delivery were assigned into two groups i.e Group 1 and Group 2. Gp1 were treated with oral prostaglandin E1 analog misoprostol (400ugm) and Gp2 were treated intravenously with methyl ergometrine (0.2 mg); both after delivery of anterior shoulder of baby. Results: Study revealed that there were no significant differences (p=0.221) when parity, mode of delivery (p=0.668), removal of placenta (p=0.500) and need for oxytocics (p=0.134) were considered. However, it shows significant differences in length of third stage in both groups. It was further observed that GP1 show short duration of third stage of labour and it also offers advantage over hypertension. Conclusion: Prostaglandins E1 analog (Misoprostol) can definitely bring down the incidence of maternal mortality and post partum haemorrhage.