Association of mode of delivery with maternal and perinatal outcome in SARS CoV-2 pregnancies: a retrospective observational study
Kashmira Ghosh,Neeta Sarma,Pranav N Saji,Kiriti Ranjan Dey
Background: The novel coronavirus pandemic has affected the pregnant women and newborns worldwide. It has become necessary to know the effect of mode of delivery on the mother and newborn in Covid-19 pregnancies as very few literature is found regarding this. Objective: To evaluate the association of mode of delivery with maternal and perinatal outcome in SARS CoV2 pregnancies. Methodology: Total 191 pregnant women who tested Covid positive and who delivered at a tertiary care hospital were included in the study, from July to December 2020. Maternal and perinatal outcomes in vaginal and caesarean delivery groups were compared. Results: More women delivered by caesarean section (51.3%). There is increased rate of clinical deterioration of mothers after caesarean section (p=0.03). In newborns, caesarean delivery was not found to be significantly associated with low birth weight (p=0.28) or birth asphyxia (p=0.31). 6 newborns born vaginally and 4 born by caesarean section tested positive for SARS CoV-2. Covid positive status of newborns was not significantly associated with increased risk of low birth weight (p=0.26) or neonatal sepsis (p=0.18). Statistically significant association was found between severe Covid symptoms in mothers and low birth weight of babies (p<0.0001), higher proportion of NICU admissions (p=0.0004) and early neonatal death (p=0.0005). Conclusion: There is increased rate of clinical deterioration of mothers after caesarean section but there is no association with increased need of NICU admissions or Covid-19 infection in newborns.