The New Indian Journal of OBGYN. 10(2):388-395

Fetomaternal outcome of pregnancy with hemoglobinopathy

Bivarani Goswami, Panchanan Das, K. Monesha

ABSTRACT

Objectives: The objectives of this study are to determine the obstetric and neonatal outcome in pregnancy with hemoglobinopathy. Methods and materials: A prospective observational study to evaluate maternal and neonatal outcome in pregnant women with hemoglobinopathy. The medical data of the study group attending antenatal OPD/emergency and delivering at Guwahati medical college and hospital between August 1st, 2021 to 31st July, 2022 were extracted and recorded in the proforma. Results: A total of 200 pregnant women with hemoglobinopathy were included in the study. Among the various types of hemoglobinopathy HbE homozygous constituted the highest with 39% (n=78). Among obstetric outcomes preterm (35.9%, n=14) and caesarean delivery (60%, n=23), maternal complications (87.2%,n=34) were higher in patients with HbE with beta Thalassemia trait. Low birth weight (62.1%,n=46), NICU admission (54.1%,n=40) were higher in HbE homozygous group. Conclusion: In our study patients with feto-maternal complications were higher in patients having HbE with beta thalassemia but there were no maternal mortality or stillbirth in the study population.