The New Indian Journal of OBGYN. 12(1):50-54

Timing of oxytocin injection during lower segment caesarean section and its relation to uterine contractility and patient hemodynamics

Hemapriya L, Anil Kumar, Hiteshi V Murthy

ABSTRACT

Objectives: Oxytocin is the first line uterotonic recommended by the WHO for prevention of postpartum haemorrhage. Our study aims to determine the best time of oxytocin administration during lower segment caesarean section and its effect on hemodynamic parameters and neonatal APGAR scores. Methodology: We conducted a prospective randomised trial at JSS hospital, Mysore, from April to September 2021, after obtaining approval from the institutional ethical committee. All women between 18 and 35 years of age undergoing LSCS at >34 weeks of gestation were randomised into three groups, where 10 IU oxytocin was given intramuscular just before skin incision, just before uterine incision and soon after baby extraction. The uterine tone, pulse rate, blood pressure and neonatal APGAR scores were documented. Results: Oxytocin administered just before uterine incision or after baby extraction was associated with better uterine contractility than administration before skin incision. There was no significant difference in hemodynamic parameters or neonatal APGAR in any of the groups. Conclusion: Oxytocin as the first line uterotonic administered 10 IU intramuscular at the time of uterine incision or soon after foetal extraction is effective in maintaining adequate uterine tonicity and preventing postpartum haemorrhage.